Drug Design Group
pharmfac Faculty of Pharmacy
Medical University of Sofia
2 Dunav st.,
1000 Sofia, Bulgaria

Drug Design Group

Current projects:

Novel acetylcholinesterase inhibitors for treatment of Alzheimer's disease. GRANTS: DN 03/9/2016 Bulgarian Science Fund and 10-S/2016 Medical Research Council, Medical University of Sofia

Results are published in:

Doytchinova IA, Atanasova M, Valkova I, Stavrakov G, Philipova I, Zhivkova Z, Zheleva-Dimitrova D, Konstantinov S, Dimitrov I. Novel hits for acetylcholinesterase inhibition derived by docking-based screening on ZINC database. J. Enz. Inh. Med. Chem., 33, 768-776, 2018.

Associations between food allergens and HLA-DRB1 polymorphism. GRANT: 37/2016 Medical Research Council, Medical University of Sofia

In vitro and in vivo studies of a newly synthesized galantamine derivative with potent anticholinesterase activity. GRANT: D-78/2017 Medical Research Council, Medical University of Sofia