pharmfac Faculty of Pharmacy
Medical University of Sofia
2 Dunav st.,
1000 Sofia, Bulgaria

Drug Design Group

Drug design means creation of ligand molecules binding to a target macromolecule and eliciting pharmacological effect. In order to bind, the small molecule should be complementary in shape and charge to the active site of the macromolecule.

Drug design makes the process of drug development more efficient. Modern drug design applies a variety of computer modeling techniques and often referred to as computer-aided drug design.

The Drug Design Group at the Faculty of Pharmacy employs and develops computer-based drug design methods to aid the rational synthesis of new compounds and to predict T-cell epitopes. Our models for T-cell epitope prediction are implemented in several servers.